Kosmoderma

Polyneucleotide Skin & Scalp Rejuvenation

Polyneucleotide therapy uses purified nucleotide chains derived from marine DNA to stimulate cellular repair, collagen production, and microcirculation. It helps improve skin texture, fade scars and pigmentation, and revive thinning hair by strengthening follicles. The minimally invasive treatment delivers natural, progressive results with little downtime and is suitable for most skin and scalp types.

3–5

No of Sessions

<60mins

Treatment Time

Minimal

Down Time

What is Polyneucleotide Therapy?

Polynucleotide therapy uses short DNA/RNA fragments (polynucleotide chains) derived from marine sources to trigger tissue repair and regeneration. These molecules act as biological signals that stimulate fibroblasts, boost collagen and elastin synthesis, and improve microcirculation—restoring firmness, hydration, and skin tone while helping hair follicles recover and grow.

How does it work?

When introduced into the dermis or scalp, polynucleotides bind to cellular receptors and activate repair pathways. This enhances fibroblast activity, increases extracellular matrix production, and improves blood flow. Over weeks, damaged tissue remodels, scars soften, fine lines smooth out, and hair follicles receive better nourishment—producing gradual, natural-looking rejuvenation.

Why To Choose Kosmoderma?

4.9

Google Ratings

Polyneucleotide Therapy for Women

Skin and Hair Concerns That Polynucleotides Can Help With

Polynucleotide therapy is a gentle, science-driven way to restore skin glow and encourage hair growth. For women, it treats early aging, dullness, acne marks, and thinning—delivering smoother skin and healthier hair over a course of sessions.

  • Hair thinning
  • Excessive hair fall
  • Acne marks
  • Uneven skin tone
  • Dull skin
  • Tired skin
  • Fine lines and early ageing
  • Dryness or loss of glow

Polyneucleotide Therapy for Men

Skin and Scalp Concerns That Polynucleotides Can Improve

Men commonly face hair thinning, sun damage, and rough texture. Polyneucleotide therapy strengthens hair roots, improves scalp health, and repairs sun-affected skin. It reduces visible signs of wear and restores a firmer, more even skin surface — all with minimal interruption to daily life.

  • Hair loss
  • Weak hair roots
  • Sun damage and tanning
  • Acne scars
  • Rough skin texture
  • Dull skin
  • Dehydrated skin
  • Uneven tone

Polyneucleotide Therapy at Kosmoderma

Your Skin and Hair Renewal Journey

Consultation Before Treatment at Kosmoderma

Prep for the Best Results

Before treatment, our doctor will assess your skin or scalp and discuss goals — whether you want firmer skin, scar reduction, or improved hair density. We explain the treatment, expected timelines, and safety considerations. You may be asked to pause strong topical agents or recent resurfacing procedures for a short period.

  • Share your medical history and ongoing treatments
  • Drink enough water and eat well before the session
  • Avoid alcohol and smoking for a day or two
  • Wash your hair or face before coming for the treatment
Consultation Before Treatment at Kosmoderma

Gentle and Focused Care

We cleanse the area and use microinjections or microneedling to deliver the polynucleotide serum into precise skin or scalp layers. Topical numbing can be applied to ensure comfort. The clinician adjusts depth and dose based on skin or scalp condition for safe, even coverage.

  • The polynucleotide serum is applied evenly across the target area
  • The doctor adjusts the depth and amount based on your skin or scalp type
  • Cooling or a gentle massage may be done to soothe the skin
  • The whole session usually takes about 30–45 minutes
Consultation Before Treatment at Kosmoderma

Calm, Heal, and Glow

After treatment, we soothe the area with a calming gel. Mild redness or tiny bumps may appear but settle within hours to a couple of days. Healing and remodeling continue over several weeks — visible improvement builds progressively as collagen and new tissue form.

  • Avoid washing the area for 24 hours
  • Do not use makeup, hair dye, or harsh products for a few days
  • Protect your skin from direct sunlight and always use sunscreen
  • Follow the post-care routine shared by your doctor

Kosmoderma Skin, Hair & Body Clinics

Experience. Expertise. Excellence.

Legacy of Trust

Over 20 years of excellence in advanced dermatology and aesthetic care.

Expert Care

Treatments led by MD-Certified Dermatologists with global training and experience.

Circle of Trust

All procedures use US-FDA-approved and Clinically Proven Technology for your safety.

Replenish, Revive, and Reveal Radiant Skin

Ultimate Guide to Skin Booster Treatment

Polyneucleotide Therapy

Before & After Results

Repair, hydrate, and boost hair and skin health with advanced cell signals

See how Polyneucleotide Therapy at Kosmoderma uses purified nucleotide chains to speed up tissue repair and stimulate hair follicles. Our dermatologists deliver the solution with micro-needling or targeted injections to improve texture, fade scars, and strengthen hair. Results develop over a few sessions for natural, lasting improvement.

What You Will Usually Notice

  • Brighter, more even skin tone
  • Smoother texture and softer fine lines
  • Faded acne scars and reduced pigmentation
  • Better hydration and firmer skin
  • Thicker-looking hair and less hair fall
  • Gradual, lasting improvement after a course of treatments

FAQ

Polyneucleotide Therapy Frequently Asked Question

Satisfied Clients
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What is polynucleotide therapy, and how is it different from PRP?

Polyneucleotide therapy uses purified nucleotide chains to trigger cellular repair and collagen production. Unlike PRP (platelet-rich plasma), which uses your own platelets, polynucleotide products deliver biologic signaling molecules that act directly on repair pathways—offering a complementary, cell-signaling approach.

Most patients report only mild discomfort. Topical numbing is available to reduce sensations; the procedure is well tolerated by most people.

A typical course is 3–5 sessions spaced 2–4 weeks apart. Your clinician will recommend a personalized plan based on the condition being treated.

Initial improvements in hydration and radiance are often visible within a few days; collagen remodeling and thicker hair typically appear over 4–8 weeks and continue improving after further sessions.

Minor redness, swelling, or pinpoint bruising at injection sites can occur and usually settle within a few hours to days. Serious complications are rare when performed by an experienced dermatologist.

Pregnant or breastfeeding women, patients with active skin infections, or patients on certain immunosuppressive medications should avoid treatment until medically cleared by a doctor.

Results vary by individual, but improvements in texture and hair density can last several months. Maintenance sessions every 6–12 months may be recommended to sustain outcomes.

Yes—it is often combined safely with microneedling, PRP, or topical medical-grade serums. Your doctor will design a regimen that complements your goals while ensuring safety.

Downtime is minimal. Most clients return to work the same day; avoid heavy exercise, saunas, or facial procedures for 24–48 hours as advised.

Share your medical history, pause strong topical treatments if advised, avoid alcohol and heavy sun exposure before the session, and arrive with a clean face or scalp.